Pharmacokinetics & Pharmacodynamics of Sneha Dravyas

Snehana (Oleation) – Part 3

Prepared  on 31 Oct 15

Pharmacokinetics & Pharmacodynamics of Sneha Dravyas

a.  Guru (Heaviness) : This quality of oily substance bring heaviness, increase malas, increase body mass index. Hence useful in wasting conditions like Tuberculosis, Anemia of chronic diseases, Cancers & HIV

•      Because of this quality, oily substances are not digest easily. It means they last in GI Tract for a longer duration. This produces early satiety ( Satisfaction or Trupti in Marathi)

•      Snehan dravyas are High Calorie substances.So must use carefully in obese patients or High Cholesterol patients.But then vaidya can use Medicated Ghee or oil.

•      These substances increase kapha dosha and decrease vata dosha level. So they are useful in Dhatu kshaya janya vata Prakop ( Degenerative Vata Problems)

•      These substances have Predominance of prithvi( Earth) and apa mahabhuta( Water).So they are Bruhan i.e Nutritive in action

b.  Snigdha (Oiliness) : Substances lubricates the channel in the body.They nourish Schlek ,Bodhak ,Tarpak Kapha. Useful in Osteoarthritis, Parkinson, Alzheimer

•      They have Predominance of apa mahabhuta. This property is used in Vata conditions like Dryness of the skin or wrinkling of the skin in ageing process.

c.   Mand (Slow moving) : These substances slow down the process of Degeneration .They work as Anti ageing . Hence medicated Ghees & Oils are used in Degenerative diseases like osteoarthritis ( Narayan oil ) , Alzheimer ( Natsya & Internally Brahmi Ghruta)  & Autoimmune diseases like Psoriasis (Mahatiktak Ghutam) or Rheumatoid arthritis ( Pinda Taila,Castor Oil).

•      Sukshma (Minuteness / easily penetrating) : The Oily substances can penetrate smallest channels because of this quality. They have Predominance of Aakash( Ether) mahabhuta. These Substances can cross the biological membranes very easily like BBB ( Blood Brain Barrier) .

•      To target the neurological sites Ghrutum or Oils are preferred as they are the good vehicles and drugs & can cross the Blood Brain Barrier. e.g. In Bipolar disorder, Anxiety, Alzheimer's & Parkinson's disease Brahmi Ghrtum is used for Nasya or for internal use.

•      Mandukparni, Guduchi, Shankhapushpi, Jyotishmati is used as Medhya Rasayana in the form of Ghee to modify the cognitive brain functions.

d.  Mrudu (Softness) : Because of this quality, oily substance destroys strong binding of atomic particles of a rigid material. So they are helpful to remove stiffness ,which is seen in many muscular problems like Backache, Neck pain, Joint stiffness

e.  Dravam (Liquidity) : Liquid in nature. They have spreading nature.

•      Pichhila (Sticky) : Sticky in nature.It is useful in osteoarthritis to prevent the degeneration of articular cartilage and its healing process.

Prof.Dr.R.R.Deshpande --- 9226810630

Dr.Sachin Sarpotdar -------- 9822795363

Dr,Mayura Shinde ---------- 7276866831